04 Mar

Immunoglobulins

Specific cells of the immune system called B-cells make specialized proteins called antibodies.  When an antigen is introduced into an animal antibodies called immunoglobulins are produced that are specific for the bacterial antigens.  Immunoglobulins are present in the circulating blood of immunized animals.  If blood cells from cush animals are separated from the liquid portion of blood, the clear liquid that remains has the immunoglobulins and is called antiserum.  Some antibodies that are available commercially are conjugated to enzymes that induce a color change in a solution when presented with the appropriate substrate.  In order to make an antibody antigens are introduced in a specific animal.  The animal is then bled and the immunoglobulins are purified from the blood serum. pauln