08 Apr

Differential WBC Count

A differential white blood cell count or differential WBC count can be used to determine which infectious disease is present in an individual.  In 1883 Elie Metchnikoff puplished the phagocytic theory of immunity.  He postulated that large cells in the tissue fluid and blood of animals were the first line of defense against foreign bodies.  He stated that the larger cells were macrophages and the smaller ones were microphages.  Neutrophils make up roughly 50-70% of the cells in blood, lymphocytes make up 20-30%, monocytes 2-6%, eosinophils 1-5% and basophils less than 1%.  A normal white blood cell count is between 5,000 and 10,000 white blood cells per cubic millimeter.  High white blood cell counts are referred to as leukocytosis.  When counts fall below 5,000 leukopenia is said to exist.  pauln