15 Apr

Value of a Differential Count

The value of a differential count is immeasurable in the diagnosis of infectious diseases.  High neutrophil counts, or neutrophilia, often signals localized infections, such as appendicitis or abscesses in some other part of the body.  Neutropenia, a condition in which there is a marked decrease in the numbers of neutrophils, occurs in typhoid fever, undulant fever, and influenza.  Eosinophilia may indicate allergic conditions or invasions of parasitic roundworms such as Trichinella spiralis, the “pork worm.”  Counts of eosinophils may rise to as high as 50% in cases of trichinosis.  High lymphocyte counts, or lymphocytosis, are present in whooping cough and some viral inections.  Increased  numbers of monocytes, or monocytosis, may indicate the presence of the Epstein-Barr virus, which causes infectious mononucleosis. pauln